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obestatyna
trzustka
fizjologia
oddziaływanie
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Abstrakt
W tej pracy opisane zostaną po krótce dwa hormony wpływające na fizjologiczne funkcjonowanie trzustki. Obestatyna i grelina to peptydy oddziałujące antagonistycznie wywierając wpływ na homeostazę glukozy w organizmie. Jak powszechnie wiadomo, zaburzenia metabolizmu glukozowego stoją u podstaw wielu schorzeń. Jednymi z najbardziej znanych są cukrzyca typu II oraz otyłość, stanowiące obecnie problem globalny. Ponad to nadmiar tkanki tłuszczowej może prowadzić do konsekwencji takich jak nowotworzenie w obrębie narządów układu pokarmowego[1]. Wysoce istotna wydaje się zatem rola obestatyny i greliny. Zdobyta w tym zakresie wiedza posłużyć może w poszukiwaniu rozwiązań terapeutycznych lub zapobiegawczych.
Bibliografia
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