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- 29-04-2021 (3)
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Abstract
Ponad 20% zachorowań na nowotwory w grupie kobiet w Polsce, jak i na świecie stanowią nowotwory piersi. Celem pracy była ocena wpływu anatomii i kształtu piersi w grupie pacjentek z nowotworem piersi lewej poddanych teleradioterapii, na dawki promieniowania jonizującego dostarczane do tkanek zdrowych. Analizą zostało objętych 50 pacjentek, które były poddane leczeniu, z powodu nowotworu lewej piersi, metodą trójwymiarowej radioterapii konformalnej. Do oceny wpływu anatomii pacjentek na dawki dostarczane do tkanek zdrowych: płuc i serca wykorzystano analizę histogramów dawka-objętość. Po przeprowadzaniu szczegółowej analizy stwierdzono, że na dawki w płucach i w sercu największy wpływ ma kształt piersi oraz wielkość CTV. Nie odnotowano wpływu kształtu oraz wielkości klatki piersiowej na dawki w narządach krytycznych. Dla pacjentek posiadających duże piersi opadające, korzystne jest stosowanie innych niż standardowe unieruchomienia np. pozycja na brzuchu.
References
Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.
Moran MS, Schnitt SJ, Giuliano AE, et al. Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. Ann Surg Oncol. 2014; 21:704-16.
Darby S, McGale P, Correa C, et al. Review Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Early Breast Cancer Trialists' Collaborative Group (EBCTCG)., Lancet. 2011; 378:1707-16.
Chen S.N, Ramachandran P, Deb P. Dosimetric comparative study of 3DCRT, IMRT, VMAT, Ecomp, and Hybrid techniques for breast radiation therapy Radiat Oncol J. 2020;38: 270–81.
. Zhang Q, Yu XL, Hu WG, et al. Dosimetric comparison for volumetric modulated arc therapy and intensity-modulated radiotherapy on the left-sided chest wall and internal mammary nodes irradiation in treating post-mastectomy breast cancer. Radiol Oncol. 2015; 49:91-8.
Nantavithya C, Saksornchai K, Oonsiri P et al. Dosimetric study of three-dimensional conformal radiotherapy, electronic compensator technique, intensity-modulated radiation therapy and volumetric-modulated arc therapy in whole breast irradiation. Radiother Pract. 2017;16:431–43.
Bentzen S.M, Constine L.S, Deasy J.O, et al. Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): An Introduction to the Scientific Issues. Int J Radiat Oncol Biol Phys. 2010;76:3–9.
ICRU Report 50. Prescribing, Recording and Reporting Photon Beam Therapy. International Commission on Radiation Units and Measurements 1993,
ICRU Report 62. Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU Report 50). International Commission on Radiation Units and Measurements 1999,
Gagliardi G, Constine L. S, Moiseenko V, et al. Radiation dose – volume effects in the heart, Int J Radiat Oncol Biol Phys. 2010;76:77-85.
Drost L, Yee C, Lam H, et al. A Systematic Review of Heart Dose in Breast Radiotherapy, Clin Breast Cancer, 2018 Clin Breast Cancer 2018;18:819-24.
Hannan R, Thompson R.F, Chen Y, et al. Hypofractionated Whole-Breast Radiation Therapy: Does Breast Size Matter? Int J Radiat Oncol Biol Phys. 2012;84:894-901.
Kundrát P, Simonetto C, Eidemüller M, et al. What anatomic features govern personal long-term health risks? Radiat Prot Dosimetry 2019;186:381-5.
Stewart D, Ambat J, Wallis S, et al. Breast radiotherapy using a breast cup: moving the target, not the patient. Pract Radiat Oncol. 2020;10:238-43.
Takahashi K, Morota M, Kagami Y, et al. Prospective study of postoperative whole breast radiotherapy for Japanese large-breasted women: a clinical and dosimetric comparisons between supine and prone positions and a dose measurement using a breast phantom, BMC Cancer. 2016;16:757
Yao S, Zhang Y, Nie K, Setup uncertainties and the optimal imaging schedule in the prone position whole breast radiotherapy Radiat Oncol. 2019;14:76.
Shah C, Badiyan S, Berry S, et al. Cardiac dose sparing and avoidance techniques in breast cancer radiotherapy, Radiother Oncol. 2014;112:9-16.
Lai J, Hu S, Luo Y, et al. Meta-analysis of deep inspiration breath hold (DIBH) versus free breathing (FB) in postoperative radiotherapy for left-side breast cancer, Breast Cancer. 2020;27:299-307.
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