Abstrakt
Rolą teranostyki jest indywidualizacja postępowania diagnostycznego i leczniczego. Obecnie teranostyka znajduje najszersze zastosowanie w monitorowaniu i leczeniu guzów neuroendokrynnych i raka stercza. Istotą teranostyki jest dobór wskaźników preparatów radiofarmaceutycznych, umożliwiających obrazowanie i leczenie choroby. Wśród wyjątkowych w teranostyce radioizotopów, dodatkowo należy lutet-177 i aktyn-225.
Bibliografia
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Kabasakal L, Toklu T, Yeyin N, Demirci E, Abuqbeitah M, Ocak M, Aygün A, Karayel E, Pehlivanoğlu H, Alan Selçuk N. Lu-177-PSMA-617 Prostate-Specific Membrane Antigen Inhibitor Therapy in Patients with Castration-Resistant Prostate Cancer: Stability, Bio-distribution and Dosimetry. Mol Imaging Radionucl Ther. 2017 Jun 1;26(2):62-68. doi: 10.4274/mirt.08760. PMID: 28613198; PMCID: PMC5472088.
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Hooijman EL, Chalashkan Y, Ling SW, Kahyargil FF, Segbers M, Bruchertseifer F, Morgenstern A, Seimbille Y, Koolen SLW, Brabander T, de Blois E. Development of [225Ac]Ac-PSMA-I&T for Targeted Alpha Therapy According to GMP Guidelines for Treatment of mCRPC. Pharmaceutics. 2021 May 13;13(5):715. doi: 10.3390/pharmaceutics13050715. PMID: 34068206; PMCID: PMC8153125.
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Eissa A, Elsherbiny A, Coelho RF, Rassweiler J, Davis JW, Porpiglia F, Patel VR, Prandini N, Micali S, Sighinolfi MC, Puliatti S, Rocco B, Bianchi G. The role of 68Ga-PSMA PET/CT scan in biochemical recurrence after primary treatment for prostate cancer: a systematic review of the literature. Minerva Urol Nefrol. 2018 Oct;70(5):462-478. doi: 10.23736/S0393-2249.18.03081-3. Epub 2018 Apr 17. PMID: 29664244.
Sanli Y, Simsek DH, Sanli O, Subramaniam RM, Kendi AT. 177Lu-PSMA Therapy in Metastatic Castration-Resistant Prostate Cancer. Biomedicines. 2021 Apr 15;9(4):430. doi: 10.3390/biomedicines9040430. PMID: 33921146; PMCID: PMC8071500.
Kratochwil C, Bruchertseifer F, Giesel FL, Weis M, Verburg FA, Mottaghy F, Kopka K, Apostolidis C, Haberkorn U, Morgenstern A. 225Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer. J Nucl Med. 2016 Dec;57(12):1941-1944. doi: 10.2967/jnumed.116.178673. Epub 2016 Jul 7. PMID: 27390158.
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Prawa autorskie (c) 2023 Zeszyty Naukowe Wielkopolskiego Centrum Onkologii